How Do People Get Infected with Capnocytophaga? | Capnocytophaga | CDC
Capnocytophaga canimorsus, found in the normal oral flora of dogs, has the potential to cause conditions ranging from with complete splenic infarction and thrombotic . have been specifically linked to dog and cat bites or. Capnocytophaga bacteria (germs) can spread to people through bites, scratches, licks Drink alcohol excessively; Have had their spleens removed; Have HIV. Bacteria found in the saliva of dogs and cats killed a Wisconsin woman and left by the CDC, such as substance abuse or the absence of a spleen. cases of capnocytophaga infection do not have to be reported to the CDC.
Postsplenectomy infection - strategies for prevention in general practice.
Capnocytophaga species - Infectious Disease and Antimicrobial Agents
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J Clin Rheumatol ;7: Roscoe D, Clarke A. Capnocytophaga canimorsus prosthetic aortitis in an HIV-positive woman. Acta Med Port ; Sarma PS, Mohanty S. Shahani L, Khardori N. BMJ Case Rep ; J Infect Dis ; Microbiology of mandibular third molar pericoronitis: In incidents where the patient is in full septic shock, whole blood smears may be effective. Irrigation of wounds with saline is recommended and individuals are encouraged to seek medical help for the administration of antibiotics. Antibiotics are recommended if wounds are deep or individuals prolong seeking medical attention.
Antibiotics that contain beta-lactamase inhibitors i. It has shown resistance to gentamicin. For cases of septicemia, high doses of penicillin are required. Third-generation cephalosporins are often given prior to diagnosis because they cover a broad range of Gram-negative bacteria.
After diagnosis, provided the strain is not beta-lactamase producing, medication should be switched to penicilin G.
Mortality of meningitis-related infections is much lower than mortality associated with septicemia. Evasion of immune system[ edit ] C. Macrophages recognize and kill pathogens by engulfing them. They also secrete cytokines necessary to begin the immune pathway cascade.
In cells infected with C. This suggests that C.
In fact, in the presence of PMNs, C. Greater knowledge about the pathogenesis of this bacillus is required to prevent and treat the diseases associated with it. Capnocytophaga canimorsus Septicemia in Denmark, Review of 39 Cases. Clinical Infectious Diseases Journal of Clinical Microbiology 27 2: Infection and Immunity 63 9: Capnocytophaga canimorsus Infections in Human: Review of the Literature and Cases Report.
European Journal of Epidemiology 12 5: After becoming febrile, he developed microangiopathic hemolytic anemia and hemodynamic instability, and soon after was intubated due to hypoxic respiratory failure and decreased consciousness.
Plasma exchange was initiated but subsequently stopped when positive blood cultures grew a gram-negative organism. The patient progressively improved following therapy with piperacillin-tazobactam, which was switched to imipenem, then meropenem when Capnocytophaga was identified. Conclusions There is a common misconception amongst practitioners that the presence of systemic infection excludes the possibility of TTP and vice versa. This case emphasizes that TTP may occur secondary to a systemic infection, thereby allowing the two processes to coexist.
It is important to maintain a wide differential when considering the diagnosis of either TTP or C. Capnocytophaga canimorsus, Thrombotic thrombocytopenic purpura, Splenic infarction, Dog bite Background Animal bites are a common occurrence and usually involve dogs and cats, with the majority being minor and requiring no medical attention.
However, in certain rare cases, an infection introduced by such a bite can be fatal. The genus Capnocytophaga consists of seven species, with only Capnocytophaga cynodegmi and Capnocytophaga canimorsus being considered human pathogens, both of which can be found in the normal oral flora of dogs and less commonly that of cats [ 1 ]. Identification of the organism is further complicated by its fastidious nature and difficulty to culture.
In this patient subset an overwhelming infection can progress to multiple organ system failure and death within twenty-four hours, making early recognition is critical to survival.